Structured Summary
Abstract
Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic FACIES; HIRSUTISM; VIRILIZATION; multiple endocrine abnormalities, and early death.
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Classification
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Synonyms
9 entry terms
- Leprechaunism
- Leprechaunisms
- Syndrome, Donohue
- Mendenhall Syndrome
- Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities
- Rabson-Mendenhall Syndrome
- Rabson Mendenhall Syndrome
- Syndrome, Mendenhall
- Syndrome, Rabson-Mendenhall
MeSH Record
Aspects Covered
34 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
History Note
2010
MeSH Record
Previous Indexing
- Abnormalities, Multiple (2002-2009)
- Acanthosis Nigricans (2002-2009)
- Diabetes Mellitus (2000-2009)
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AMA Style
References
- National Library of Medicine. Donohue Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D056731. http://id.nlm.nih.gov/mesh/2026/D056731
- Donohue Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Donohue_syndrome
- Donohue Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q2467739