Structured Summary
Abstract
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.
Chemical Identity
Chemical Information
- Molecular Formula
- C17H22N2O
- Molecular Weight
- 270.37 g/mol
- CAS Registry No.
- 469-21-6
- IUPAC Name
- N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine
- InChIKey
- HCFDWZZGGLSKEP-UHFFFAOYSA-N
- SMILES
- CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C
- MeSH Unique ID
- D004319
- Source
- PubChem CID 3162
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(72); was see under PYRIDINES 1972-90
MeSH Record
Previous Indexing
- Antiparkinson Agents (1972)
- Pyridines (1972)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Doxylamine. Medical Subject Headings (MeSH). 2026. Unique ID D004319. http://id.nlm.nih.gov/mesh/2026/D004319
- Doxylamine. In: Wikipedia. https://en.wikipedia.org/wiki/Doxylamine
- Doxylamine. In: Wikidata. https://www.wikidata.org/wiki/Q423390
- Doxylamine. In: PubChem Compound. CID 3162. https://pubchem.ncbi.nlm.nih.gov/compound/3162