Chemicals and Drugs

Dual Specificity Phosphatase 1

A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

MeSH Record

Classification

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MeSH Record

Synonyms

18 entry terms
  • 3CH134 Phosphatase
  • CL100 Phosphatase
  • Externally Regulated Phosphatase (ERP)
  • MAP Phosphatase-1
  • MAPK Phosphatase
  • MKP-1 Phosphatase
  • Map Kinase Phosphatase 1
  • Mitogen-Activated Protein Phosphatase-1
  • MAP Phosphatase 1
  • MKP 1 Phosphatase
  • Mitogen Activated Protein Phosphatase 1
  • Phosphatase, 3CH134
  • Phosphatase, CL100
  • Phosphatase, MAPK
  • Phosphatase, MKP-1
  • Phosphatase-1, MAP
  • Phosphatase-1, Mitogen-Activated Protein
  • Protein Phosphatase-1, Mitogen-Activated

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1992)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Dual Specificity Phosphatase 1. Medical Subject Headings (MeSH). 2026. Unique ID D054638. http://id.nlm.nih.gov/mesh/2026/D054638
  2. Dual Specificity Phosphatase 1. In: Wikidata. https://www.wikidata.org/wiki/Q21171041