Chemicals and Drugs

EGF Family of Proteins

A family of proteins that are related to epidermal growth factor. They share in common a consensus sequence consisting of six spatially conserved CYSTEINE residues which form three intramolecular bonds. This consensus sequence is commonly referred to EGF motif and is considered essential for binding of the proteins to ERB RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of proteins that are related to epidermal growth factor. They share in common a consensus sequence consisting of six spatially conserved CYSTEINE residues which form three intramolecular bonds. This consensus sequence is commonly referred to EGF motif and is considered essential for binding of the proteins to ERB RECEPTORS.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • EGF Receptor Ligands
  • Epidermal Growth Factor-Like Proteins
  • Epidermal Growth Factors
  • Epidermal Growth Factor Like Proteins
  • Ligands, EGF Receptor
  • Proteins EGF Family
  • Receptor Ligands, EGF

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2015; for EPIDERMAL GROWTH FACTORS use EPIDERMAL GROWTH FACTOR 1981-2014

MeSH Record

Previous Indexing

  • Epidermal Growth Factor (1981-2014)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. EGF Family of Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D066255. http://id.nlm.nih.gov/mesh/2026/D066255
  2. EGF Family of Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24783852