Diseases

Encephalomalacia

Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)

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MeSH Record

Synonyms

7 entry terms
  • Cerebromalacia
  • Cerebromalacias
  • Encephalomalacias
  • Encephalomalacia, Multicystic
  • Multicystic Encephalomalacia
  • Encephalomalacias, Multicystic
  • Multicystic Encephalomalacias

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1966(1964)

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NLM Classification

WL 348

AMA Style

References

  1. National Library of Medicine. Encephalomalacia. Medical Subject Headings (MeSH). 2026. Unique ID D004678. http://id.nlm.nih.gov/mesh/2026/D004678
  2. Encephalomalacia. In: Wikipedia. https://en.wikipedia.org/wiki/Encephalomalacia
  3. Encephalomalacia. In: Wikidata. https://www.wikidata.org/wiki/Q947813