Diseases

Periventricular Leukomalacia

Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

23 entry terms
  • Encephalomalacia, Periventricular
  • Leucomalacia, Periventricular
  • Leukomalacia, Periventricular
  • Encephalomalacias, Periventricular
  • Leucomalacias, Periventricular
  • Leukomalacias, Periventricular
  • Periventricular Encephalomalacia
  • Periventricular Encephalomalacias
  • Periventricular Leucomalacia
  • Periventricular Leucomalacias
  • Periventricular Leukomalacias
  • Cystic Periventricular Leukomalacia
  • Neonatal Cerebral Leukomalacia
  • Cerebral Leukomalacia, Neonatal
  • Cerebral Leukomalacias, Neonatal
  • Cystic Periventricular Leukomalacias
  • Leukomalacia, Cystic Periventricular
  • Leukomalacia, Neonatal Cerebral
  • Leukomalacias, Cystic Periventricular
  • Leukomalacias, Neonatal Cerebral
  • Neonatal Cerebral Leukomalacias
  • Periventricular Leukomalacia, Cystic
  • Periventricular Leukomalacias, Cystic

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

periventricular refers to the cerebral ventricles

MeSH Record

History Note

1991(1987)

MeSH Record

Previous Indexing

  • Cerebral Hemorrhage (1966-1986)
  • Cerebral Ventricles (1966-1986)
  • Encephalomalacia (1966-1986)
  • Infant, Newborn (1966-1986)
  • Infant, Premature, Diseases (1966-1986)

MeSH Hierarchy

Tree Numbers

  1. C10w.228w.140w.300w.700w
  2. C10w.228w.140w.461w.550w
  3. C14w.907w.253w.612w
  4. C16w.614.521.450w

AMA Style

References

  1. National Library of Medicine. Periventricular Leukomalacia. Medical Subject Headings (MeSH). 2026. Unique ID D007969. http://id.nlm.nih.gov/mesh/2026/D007969
  2. Periventricular Leukomalacia. In: Wikipedia. https://en.wikipedia.org/wiki/Periventricular_leukomalacia
  3. Periventricular Leukomalacia. In: Wikidata. https://www.wikidata.org/wiki/Q469490