Chemicals and Drugs

Enoyl-CoA Hydratase

An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

24 entry terms
  • 3-Hydroxyacyl CoA Hydrolyases
  • 3-Hydroxyacyl Dehydratases
  • Crotonase
  • Enoyl CoA Hydratases
  • Enoyl Hydrase
  • beta-Hydroxyacyl Dehydratases
  • beta-Hydroxyacyl-CoA Dehydrases
  • trans-2-Enoyl-Coenzyme A Hydratase
  • 3 Hydroxyacyl CoA Hydrolyases
  • 3 Hydroxyacyl Dehydratases
  • CoA Hydratases, Enoyl
  • CoA Hydrolyases, 3-Hydroxyacyl
  • Dehydrases, beta-Hydroxyacyl-CoA
  • Dehydratases, 3-Hydroxyacyl
  • Dehydratases, beta-Hydroxyacyl
  • Enoyl CoA Hydratase
  • Hydrase, Enoyl
  • Hydratase, Enoyl-CoA
  • Hydratase, trans-2-Enoyl-Coenzyme A
  • Hydratases, Enoyl CoA
  • Hydrolyases, 3-Hydroxyacyl CoA
  • beta Hydroxyacyl CoA Dehydrases
  • beta Hydroxyacyl Dehydratases
  • trans 2 Enoyl Coenzyme A Hydratase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

97; was ENOYL COA HYDRATASES 1978-96 (see under HYDRO-LYASES 1978-90)

MeSH Record

Previous Indexing

  • Coenzyme A (1966-1977)
  • Hydro-Lyases (1966-1977)

MeSH Hierarchy

Tree Number

  1. D08.811w.520w.241.300w.250w

AMA Style

References

  1. National Library of Medicine. Enoyl-CoA Hydratase. Medical Subject Headings (MeSH). 2026. Unique ID D004746. http://id.nlm.nih.gov/mesh/2026/D004746
  2. Enoyl-CoA Hydratase. In: Wikipedia. https://en.wikipedia.org/wiki/Enoyl-CoA_hydratase
  3. Enoyl-CoA Hydratase. In: Wikidata. https://www.wikidata.org/wiki/Q5379472