Chemicals and Drugs

Epithelial Sodium Channels

Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

24 entry terms
  • ENaC (Epithelial Na+ Channel)
  • Epithelial Amiloride-Sensitive Sodium Channel
  • Epithelial Sodium Channel
  • Epithelial Sodium Ion Channels
  • Epithelial Amiloride Sensitive Sodium Channel
  • Sodium Channel, Epithelial
  • Sodium Channels, Epithelial
  • ENaC alpha
  • ENaC beta
  • ENaC delta
  • ENaC gamma
  • Epithelial Sodium Channel, alpha Subunit
  • Epithelial Sodium Channel, beta Subunit
  • Epithelial Sodium Channel, delta Subunit
  • Epithelial Sodium Channel, gamma Subunit
  • SCNN1 alpha Subunit
  • SCNN1 beta Subunit
  • SCNN1 delta Subunit
  • SCNN1 gamma Subunit
  • Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit
  • Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit
  • Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit
  • Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit
  • alpha Subunit, SCNN1

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013(1995)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.875w.200w
  2. D12.776w.543w.550w.450w.875w.200w
  3. D12.776w.543w.585w.400w.875w.200w

AMA Style

References

  1. National Library of Medicine. Epithelial Sodium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D053503. http://id.nlm.nih.gov/mesh/2026/D053503
  2. Epithelial Sodium Channels. In: Wikipedia. https://en.wikipedia.org/wiki/Epithelial_sodium_channel
  3. Epithelial Sodium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q424948