Chemicals and Drugs

Extracellular Signal-Regulated MAP Kinases

A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.

MeSH Record

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MeSH Record

Synonyms

16 entry terms
  • ERK MAP Kinase
  • ERK MAP Kinases
  • Extracellular Signal-Regulated Kinase
  • Extracellular Signal-Regulated Kinases
  • Extracellular Signal-Regulated MAP Kinase
  • MAP Kinases, Extracellular Signal-Regulated
  • Extracellular Signal Regulated Kinase
  • Extracellular Signal Regulated Kinases
  • Extracellular Signal Regulated MAP Kinase
  • Extracellular Signal Regulated MAP Kinases
  • Kinase, ERK MAP
  • Kinase, Extracellular Signal-Regulated
  • Kinases, Extracellular Signal-Regulated
  • MAP Kinase, ERK
  • MAP Kinases, Extracellular Signal Regulated
  • Signal-Regulated Kinase, Extracellular

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

note specifics

MeSH Record

History Note

2005; for EXTRACELLULAR SIGNAL-REGULATED KINASES use MITOGEN-ACTIVATED PROTEIN KINASES 1994-2004

MeSH Record

Previous Indexing

  • Mitogen-Activated Protein Kinases (1992-2004)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.567w.249w
  2. D12.776w.476.563w.567w.249w

AMA Style

References

  1. National Library of Medicine. Extracellular Signal-Regulated MAP Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D048049. http://id.nlm.nih.gov/mesh/2026/D048049
  2. Extracellular Signal-Regulated MAP Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Extracellular_signal-regulated_kinases
  3. Extracellular Signal-Regulated MAP Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q409325