Diseases

Familial Periodic Paralyses

A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)

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MeSH Record

Synonyms

11 entry terms
  • Familial Periodic Paralysis
  • Paralyses, Familial Periodic
  • Periodic Paralysis, Familial
  • Paralysis, Familial Periodic
  • Periodic Paralyses, Familial
  • Normokalemic Periodic Paralysis
  • Normokalemic Periodic Paralyses
  • Paralyses, Normokalemic Periodic
  • Paralysis, Normokalemic Periodic
  • Periodic Paralyses, Normokalemic
  • Periodic Paralysis, Normokalemic

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

a specific disease entity: see MeSH definition

MeSH Record

History Note

2000(1966)

MeSH Hierarchy

Tree Numbers

  1. C05w.651w.701w
  2. C10w.668w.491w.650w
  3. C16w.320w.565w.618w.711w
  4. C18.452w.648w.618w.711w

AMA Style

References

  1. National Library of Medicine. Familial Periodic Paralyses. Medical Subject Headings (MeSH). 2026. Unique ID D010245. http://id.nlm.nih.gov/mesh/2026/D010245
  2. Familial Periodic Paralyses. In: Wikipedia. https://en.wikipedia.org/wiki/Periodic_paralysis
  3. Familial Periodic Paralyses. In: Wikidata. https://www.wikidata.org/wiki/Q1788314