Diseases

Hypokalemic Periodic Paralysis

An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

12 entry terms
  • Familial Hypokalemic Periodic Paralysis
  • HOKPP
  • HYPOKPP
  • HYPOPP
  • Hypokalemic Periodic Paralysis, Familial
  • Paralysis, Hypokalemic Periodic
  • Periodic Paralysis- Hypokalemic
  • Primary Hypokalemic Periodic Paralysis
  • Westphall Disease
  • Periodic Paralysis Hypokalemic
  • Periodic Paralysis, Hypokalemic
  • Periodic Paralysis- Hypokalemics

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • Hypokalemia/complications (1965-1999)
  • Paralyses, Familial Periodic (1965-1999)

MeSH Hierarchy

Tree Numbers

  1. C05w.651w.701w.450w
  2. C10w.668w.491w.650w.450w
  3. C16w.320w.565w.618w.711w.550w
  4. C18.452w.648w.618w.711w.550w

AMA Style

References

  1. National Library of Medicine. Hypokalemic Periodic Paralysis. Medical Subject Headings (MeSH). 2026. Unique ID D020514. http://id.nlm.nih.gov/mesh/2026/D020514
  2. Hypokalemic Periodic Paralysis. In: Wikipedia. https://en.wikipedia.org/wiki/Hypokalemic_periodic_paralysis
  3. Hypokalemic Periodic Paralysis. In: Wikidata. https://www.wikidata.org/wiki/Q622828