Structured Summary
Abstract
A naturally occurring furocoumarin, found in PSORALEA. After photoactivation with UV radiation, it binds DNA via single and double-stranded cross-linking.
Chemical Identity
Chemical Information
- Molecular Formula
- C11H6O3
- Molecular Weight
- 186.16 g/mol
- CAS Registry No.
- 66-97-7
- IUPAC Name
- furo[3,2-g]chromen-7-one
- InChIKey
- ZCCUUQDIBDJBTK-UHFFFAOYSA-N
- SMILES
- C1=CC(=O)OC2=CC3=C(C=CO3)C=C21
- MeSH Unique ID
- D005363
- Source
- PubChem CID 6199
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- Psoralen
- Psoralene
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
do not confuse entry term PSORALEN, this specific drug, with PSORALENS;
MeSH Record
History Note
91(75); was see under PSORALENS 1979-90; was see under COUMARINS 1975-78
MeSH Record
Previous Indexing
- Coumarins (1966-1974)
- Furans (1966-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ficusin. Medical Subject Headings (MeSH). 2026. Unique ID D005363. http://id.nlm.nih.gov/mesh/2026/D005363
- Ficusin. In: Wikipedia. https://en.wikipedia.org/wiki/Psoralen
- Ficusin. In: Wikidata. https://www.wikidata.org/wiki/Q417788
- Ficusin. In: PubChem Compound. CID 6199. https://pubchem.ncbi.nlm.nih.gov/compound/6199