Chemicals and Drugs

Fluocinonide

A topical glucocorticoid used in the treatment of ECZEMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A topical glucocorticoid used in the treatment of ECZEMA.

Chemical Identity

Chemical Information

Molecular Formula
C26H32F2O7
Molecular Weight
494.5 g/mol
CAS Registry No.
356-12-7
IUPAC Name
[2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate
InChIKey
WJOHZNCJWYWUJD-IUGZLZTKSA-N
SMILES
CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3C[C@@H](C5=CC(=O)C=C[C@@]54C)F)F)O)C)OC(O2)(C)C
MeSH Unique ID
D005447
Source
PubChem CID 9642

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • Fluocinolide
  • Fluocinolone Acetonide 21-Acetate
  • Fluocinonide FAPG
  • Acetonide 21-Acetate, Fluocinolone
  • FAPG, Fluocinonide
  • Fluocinolone Acetonide 21 Acetate
  • Klariderm
  • Lidemol
  • Lidex
  • Lyderm
  • Metosyn
  • Novoter
  • Tiamol
  • Topsym
  • Topsyn
  • Topsyne

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under FLUOCINOLONE ACETONIDE 1975-90

MeSH Record

Previous Indexing

  • Acetic Acids (1972-1974)
  • Fluocinolone Acetonide (1972-1974)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.370w.325w
  2. D04w.210.500w.908.394w.300w

AMA Style

References

  1. National Library of Medicine. Fluocinonide. Medical Subject Headings (MeSH). 2026. Unique ID D005447. http://id.nlm.nih.gov/mesh/2026/D005447
  2. Fluocinonide. In: Wikipedia. https://en.wikipedia.org/wiki/Fluocinonide
  3. Fluocinonide. In: Wikidata. https://www.wikidata.org/wiki/Q5462791
  4. Fluocinonide. In: PubChem Compound. CID 9642. https://pubchem.ncbi.nlm.nih.gov/compound/9642