Chemicals and Drugs

Flupenthixol

A thioxanthene neuroleptic that, unlike CHLORPROMAZINE, is claimed to have CNS-activating properties. It is used in the treatment of psychoses although not in excited or manic patients. (From Martindale, The Extra Pharmacopoeia, 30th ed, p595)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thioxanthene neuroleptic that, unlike CHLORPROMAZINE, is claimed to have CNS-activating properties. It is used in the treatment of psychoses although not in excited or manic patients. (From Martindale, The Extra Pharmacopoeia, 30th ed, p595)

Chemical Identity

Chemical Information

Molecular Formula
C23H25F3N2OS
Molecular Weight
434.5 g/mol
CAS Registry No.
2709-56-0
IUPAC Name
2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
InChIKey
NJMYODHXAKYRHW-DVZOWYKESA-N
SMILES
C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
MeSH Unique ID
D005475
Source
PubChem CID 5281881

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Flupentixol
  • alpha-Flupenthixol
  • cis-Flupenthixol
  • Emergil
  • Fluanxol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under THIOXANTHENES 1975-90

MeSH Record

Previous Indexing

  • Alcohol, Ethyl (1970-1974)
  • Piperazines (1970-1974)
  • Thioxanthenes (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Flupenthixol. Medical Subject Headings (MeSH). 2026. Unique ID D005475. http://id.nlm.nih.gov/mesh/2026/D005475
  2. Flupenthixol. In: Wikidata. https://www.wikidata.org/wiki/Q420350
  3. Flupenthixol. In: PubChem Compound. CID 5281881. https://pubchem.ncbi.nlm.nih.gov/compound/5281881