Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Freeze Fracturing

Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved under high vacuum at the same temperature. The exposed surface is shadowed with carbon and platinum and coated with carbon to obtain a carbon replica.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved under high vacuum at the same temperature. The exposed surface is shadowed with carbon and platinum and coated with carbon to obtain a carbon replica.

MeSH Record

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MeSH Record

Synonyms

3 entry terms
  • Fracturing, Freeze
  • Fracturings, Freeze
  • Freeze Fracturings

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

Indexing Annotation

do not confuse with FREEZE ETCHING (wherein no cryoprotectant is used)

MeSH Record

History Note

75

MeSH Record

Previous Indexing

  • Freeze Etching (1969-1974)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.500.620.620.260
  2. E01w.370.225.750.600.620.260
  3. E05.200.500.620.620.260
  4. E05.200.750.600.620.260

MeSH Record

NLM Classification

QY 95

AMA Style

References

  1. National Library of Medicine. Freeze Fracturing. Medical Subject Headings (MeSH). 2026. Unique ID D005614. http://id.nlm.nih.gov/mesh/2026/D005614
  2. Freeze Fracturing. In: Wikidata. https://www.wikidata.org/wiki/Q3005718