Structured Summary
Abstract
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
5 entry terms
- Dibasic Processing Enzyme
- Furin Protein
- Paired Basic Amino Acid Cleaving Enzyme
- SPC1 Proteinase
- Processing Enzyme, Dibasic
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2004; use FURIN (NM) 1993-2003
MeSH Record
Previous Indexing
- Serine Endopeptidases (1989-1992)
- Subtilisins (1993-2003)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Furin. Medical Subject Headings (MeSH). 2026. Unique ID D045683. http://id.nlm.nih.gov/mesh/2026/D045683
- Furin. In: Wikidata. https://www.wikidata.org/wiki/Q581324