Chemicals and Drugs

Proprotein Convertases

Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

31 entry terms
  • Proprotein Convertase
  • Convertase, Proprotein
  • Convertases, Proprotein
  • POMC Convertase
  • POMC Enzyme
  • POMC-Converting Enzyme
  • Pro-Opiocortin Converting Enzyme
  • Pro-Opiocortin Converting Protease
  • Pro-Opiomelanocortin Converting Enzyme
  • Prohormone Convertase
  • Prohormone Convertases
  • Proopiomelanocortin Convertase
  • Proprotein Convertase, Subtilisin-Kexin Family
  • Proprotein Convertases, Subtilisin-Kexin Family
  • Subtilisin-Like Proprotein Convertases
  • Convertase, POMC
  • Convertase, Prohormone
  • Convertase, Proopiomelanocortin
  • Convertases, Prohormone
  • Convertases, Subtilisin-Like Proprotein
  • Converting Enzyme, Pro-Opiocortin
  • Converting Enzyme, Pro-Opiomelanocortin
  • Converting Protease, Pro-Opiocortin
  • POMC Converting Enzyme
  • Pro Opiocortin Converting Enzyme
  • Pro Opiocortin Converting Protease
  • Pro Opiomelanocortin Converting Enzyme
  • Proprotein Convertase, Subtilisin Kexin Family
  • Proprotein Convertases, Subtilisin Kexin Family
  • Proprotein Convertases, Subtilisin-Like
  • Subtilisin Like Proprotein Convertases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use PROPROTEIN CONVERTASES (NM) 2002-2003; for PRO-OPIOMELANOCORTIN CONVERTING ENZYME use PROPROTEIN CONVERTASES (NM) 1982-2003

MeSH Record

Previous Indexing

  • Aspartic Endopeptidases (1994-2003)
  • Peptide Peptidohydrolases (1982-1993)
  • Subtilisins (2002-2003)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Proprotein Convertases. Medical Subject Headings (MeSH). 2026. Unique ID D043484. http://id.nlm.nih.gov/mesh/2026/D043484
  2. Proprotein Convertases. In: Wikipedia. https://en.wikipedia.org/wiki/Proprotein_convertase
  3. Proprotein Convertases. In: Wikidata. https://www.wikidata.org/wiki/Q7250439