Chemicals and Drugs

Proprotein Convertase 2

A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

16 entry terms
  • Endopeptidase PC2
  • Neuroendocrine Convertase PC2
  • PC2 Endoprotease
  • PC2 Prohormone Convertase
  • PC2 Protein
  • Prohormone Convertase 2
  • Prohormone Convertase PC2
  • Prohormone Convertase, PC2
  • Proinsulin Convertase 2
  • Convertase 2, Prohormone
  • Convertase 2, Proinsulin
  • Convertase PC2, Neuroendocrine
  • Convertase PC2, Prohormone
  • Convertase, PC2 Prohormone
  • Endoprotease, PC2
  • PC2, Endopeptidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use PROPROTEIN CONVERTASE 2 (NM) 1991-2003

MeSH Record

Previous Indexing

  • Subtilisins (1991-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Proprotein Convertase 2. Medical Subject Headings (MeSH). 2026. Unique ID D045706. http://id.nlm.nih.gov/mesh/2026/D045706
  2. Proprotein Convertase 2. In: Wikidata. https://www.wikidata.org/wiki/Q7250440