Chemicals and Drugs

G(M2) Activator Protein

An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.

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See Also

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Synonyms

4 entry terms
  • GM(2) Activating Protein
  • GM2 Activator Protein
  • Hexosaminidase Activator
  • Activator Protein, GM2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005(1983)

MeSH Record

Previous Indexing

  • Proteins (1983-2004)

MeSH Hierarchy

Tree Number

  1. D08.211w.790.249w

AMA Style

References

  1. National Library of Medicine. G(M2) Activator Protein. Medical Subject Headings (MeSH). 2026. Unique ID D049289. http://id.nlm.nih.gov/mesh/2026/D049289
  2. G(M2) Activator Protein. In: Wikipedia. https://en.wikipedia.org/wiki/GM2A
  3. G(M2) Activator Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21125134