Chemicals and Drugs

Gentamicins

A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Chemical Identity

Chemical Information

Molecular Formula
C21H43N5O7
Molecular Weight
477.6 g/mol
CAS Registry No.
1403-66-3
IUPAC Name
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
InChIKey
CEAZRRDELHUEMR-UHFFFAOYSA-N
SMILES
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC
MeSH Unique ID
D005839
Source
PubChem CID 3467

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Gentamycins
  • G-Myticin
  • Garamycin
  • Gentacycol
  • Gentamicin
  • Gentamicin Sulfate
  • Gentamicin Sulfate (USP)
  • Gentamycin
  • Gentavet
  • Genticin
  • G Myticin
  • GMyticin
  • Sulfate, Gentamicin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

78; was GENTAMICIN 1963-77 (Prov 1963-65)

MeSH Hierarchy

Tree Number

  1. D09w.408w.051.374w

MeSH Record

NLM Classification

QV 350.5.G3

AMA Style

References

  1. National Library of Medicine. Gentamicins. Medical Subject Headings (MeSH). 2026. Unique ID D005839. http://id.nlm.nih.gov/mesh/2026/D005839
  2. Gentamicins. In: Wikipedia. https://en.wikipedia.org/wiki/Gentamicin
  3. Gentamicins. In: Wikidata. https://www.wikidata.org/wiki/Q422482
  4. Gentamicins. In: PubChem Compound. CID 3467. https://pubchem.ncbi.nlm.nih.gov/compound/3467