Chemicals and Drugs

Sisomicin

Antibiotic produced by Micromonospora inyoensis. It is closely related to gentamicin C1A, one of the components of the gentamicin complex (GENTAMICINS).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antibiotic produced by Micromonospora inyoensis. It is closely related to gentamicin C1A, one of the components of the gentamicin complex (GENTAMICINS).

Chemical Identity

Chemical Information

Molecular Formula
C19H37N5O7
Molecular Weight
447.5 g/mol
CAS Registry No.
32385-11-8
IUPAC Name
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
InChIKey
URWAJWIAIPFPJE-YFMIWBNJSA-N
SMILES
C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O
MeSH Unique ID
D012853
Source
PubChem CID 36119

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • 4,5-Dehydrogentamicin
  • Rickamicin
  • Sisomycin
  • Sissomicin
  • Sizomycin
  • 4,5 Dehydrogentamicin
  • Antibiotic 6640
  • Extramycin
  • Pathomycin
  • Sch-13475
  • Siseptin
  • Sisomicin Sulfate
  • Sisomicin Sulfate (2:5) Salt
  • Sch 13475
  • Sch13475

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

84(75); was see under GENTAMICINS 1978-83, was see under ANTIBIOTICS 1975-77

MeSH Record

Previous Indexing

  • Aminoglycosides (1974)
  • Antibiotics (1966-1974)
  • Glycosides (1966-1973)

MeSH Hierarchy

Tree Number

  1. D09w.408w.051.374w.785w

MeSH Record

NLM Classification

QV 350.5.G3

AMA Style

References

  1. National Library of Medicine. Sisomicin. Medical Subject Headings (MeSH). 2026. Unique ID D012853. http://id.nlm.nih.gov/mesh/2026/D012853
  2. Sisomicin. In: Wikipedia. https://en.wikipedia.org/wiki/Sisomicin
  3. Sisomicin. In: Wikidata. https://www.wikidata.org/wiki/Q3962119
  4. Sisomicin. In: PubChem Compound. CID 36119. https://pubchem.ncbi.nlm.nih.gov/compound/36119