Chemicals and Drugs

Netilmicin

Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.

Chemical Identity

Chemical Information

Molecular Formula
C21H41N5O7
Molecular Weight
475.6 g/mol
CAS Registry No.
56391-56-1
IUPAC Name
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
InChIKey
CIDUJQMULVCIBT-MQDUPKMGSA-N
SMILES
CCN[C@@H]1C[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]2[C@@H]([C@H]([C@@](CO2)(C)O)NC)O)O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N
MeSH Unique ID
D009428
Source
PubChem CID 441306

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Certomycin
  • Netillin
  • Netilmicin Sulfate
  • Netrocin
  • Netromicina
  • Netromycin
  • Netromycine
  • Nétromicine
  • Sch-20569
  • Sch 20569
  • Sch20569

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86(79); was see under GENTAMICINS 1979-85

MeSH Record

Previous Indexing

  • Gentamicins (1966-1974)
  • Sisomicin (1975-1978)

MeSH Hierarchy

Tree Number

  1. D09w.408w.051.374w.785w.525w

MeSH Record

NLM Classification

QV 350

AMA Style

References

  1. National Library of Medicine. Netilmicin. Medical Subject Headings (MeSH). 2026. Unique ID D009428. http://id.nlm.nih.gov/mesh/2026/D009428
  2. Netilmicin. In: Wikipedia. https://en.wikipedia.org/wiki/Netilmicin
  3. Netilmicin. In: Wikidata. https://www.wikidata.org/wiki/Q2553496
  4. Netilmicin. In: PubChem Compound. CID 441306. https://pubchem.ncbi.nlm.nih.gov/compound/441306