Anatomy

Germinal Center

The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • Center, Germinal
  • Centers, Germinal
  • Germinal Centers

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

96

MeSH Record

Previous Indexing

  • B-Lymphocytes (1976-1995)
  • Lymph Nodes (1968-1995)
  • Lymphocytes (1968-1995)
  • Lymphoid Tissue (1966-1995)

MeSH Hierarchy

Tree Numbers

  1. A10w.549w.400w.500w
  2. A15.382w.520w.604w.412w.500w

AMA Style

References

  1. National Library of Medicine. Germinal Center. Medical Subject Headings (MeSH). 2026. Unique ID D018858. http://id.nlm.nih.gov/mesh/2026/D018858
  2. Germinal Center. In: Wikipedia. https://en.wikipedia.org/wiki/Germinal_center
  3. Germinal Center. In: Wikidata. https://www.wikidata.org/wiki/Q1737968