Structured Summary
Abstract
A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
MeSH Record
Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- GLP-1
- Glucagon-Like Peptide-1
- GLP 1
- Glucagon Like Peptide 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2006
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Glucagon-Like Peptide 1. Medical Subject Headings (MeSH). 2026. Unique ID D052216. http://id.nlm.nih.gov/mesh/2026/D052216
- Glucagon-Like Peptide 1. In: Wikipedia. https://en.wikipedia.org/wiki/Glucagon-like_peptide-1
- Glucagon-Like Peptide 1. In: Wikidata. https://www.wikidata.org/wiki/Q424611