Chemicals and Drugs

Glutamate-Ammonia Ligase

An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Glutamate Ammonia Ligase (ADP)
  • Glutamine Synthetase
  • Glutamate Ammonia Ligase
  • Ligase, Glutamate-Ammonia
  • Synthetase, Glutamine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

95; was GLUTAMINE SYNTHETASE 1972-94

MeSH Record

Previous Indexing

  • Ligases (1966-1971)

MeSH Hierarchy

Tree Number

  1. D08.811w.464w.259.200.600w

AMA Style

References

  1. National Library of Medicine. Glutamate-Ammonia Ligase. Medical Subject Headings (MeSH). 2026. Unique ID D005974. http://id.nlm.nih.gov/mesh/2026/D005974
  2. Glutamate-Ammonia Ligase. In: Wikipedia. https://en.wikipedia.org/wiki/Glutamine_synthetase
  3. Glutamate-Ammonia Ligase. In: Wikidata. https://www.wikidata.org/wiki/Q418306