Chemicals and Drugs

Ligases

A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Ligase
  • Synthetase
  • Synthetases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

CARBOXYLASES was see under CARBOXY-LYASES & LIGASES 1964-74, was heading 1963

MeSH Hierarchy

Tree Number

  1. D08.811w.464w

MeSH Record

NLM Classification

QU 138

AMA Style

References

  1. National Library of Medicine. Ligases. Medical Subject Headings (MeSH). 2026. Unique ID D008025. http://id.nlm.nih.gov/mesh/2026/D008025
  2. Ligases. In: Wikipedia. https://en.wikipedia.org/wiki/Ligase
  3. Ligases. In: Wikidata. https://www.wikidata.org/wiki/Q410221