Chemicals and Drugs

Group V Phospholipases A2

A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Group V Secretory Phospholipase A2
  • Group V sPLA2
  • Phospholipases A2, Group V

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS

MeSH Record

History Note

2008(2001)

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.352w.100.680w.750.937w.750.775

AMA Style

References

  1. National Library of Medicine. Group V Phospholipases A2. Medical Subject Headings (MeSH). 2026. Unique ID D054505. http://id.nlm.nih.gov/mesh/2026/D054505
  2. Group V Phospholipases A2. In: Wikidata. https://www.wikidata.org/wiki/Q21173824