Structured Summary
Abstract
A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
13 entry terms
- Phospholipases A2, Secreted
- Phospholipases A2, Secretory
- SPLA2 Phospholipases
- Secreted Phospholipase A2
- Secreted Phospholipases A2
- Secretory Phospholipase A2
- sPLA(2)
- sPLA2
- sPLA2s
- A2, Secreted Phospholipase
- Phospholipase A2, Secreted
- Phospholipase A2, Secretory
- Phospholipases, SPLA2
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
MeSH Record
History Note
2008
MeSH Record
Previous Indexing
- Phospholipases A (1980-2007)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Secretory Phospholipases A2. Medical Subject Headings (MeSH). 2026. Unique ID D054497. http://id.nlm.nih.gov/mesh/2026/D054497
- Secretory Phospholipases A2. In: Wikidata. https://www.wikidata.org/wiki/Q78113079