Chemicals and Drugs

Group X Phospholipases A2

A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • GX sPLA(2)
  • Group X Secretory Phospholipase A(2)
  • Group X Secretory Phospholipase A2
  • Phospholipase A2, Group X
  • Phospholipases A2, Group X
  • sPLA(2)-X
  • sPLA2-X

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS

MeSH Record

History Note

2008(2002)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Group X Phospholipases A2. Medical Subject Headings (MeSH). 2026. Unique ID D054509. http://id.nlm.nih.gov/mesh/2026/D054509
  2. Group X Phospholipases A2. In: Wikidata. https://www.wikidata.org/wiki/Q21173823