Chemicals and Drugs

Haloperidol

A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)

Chemical Identity

Chemical Information

Molecular Formula
C21H23ClFNO2
Molecular Weight
375.9 g/mol
CAS Registry No.
52-86-8
IUPAC Name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
InChIKey
LNEPOXFFQSENCJ-UHFFFAOYSA-N
SMILES
C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
MeSH Unique ID
D006220
Source
PubChem CID 3559

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Haldol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D02w.522w.352.506w

MeSH Record

NLM Classification

QV 77.9

AMA Style

References

  1. National Library of Medicine. Haloperidol. Medical Subject Headings (MeSH). 2026. Unique ID D006220. http://id.nlm.nih.gov/mesh/2026/D006220
  2. Haloperidol. In: Wikipedia. https://en.wikipedia.org/wiki/Haloperidol
  3. Haloperidol. In: Wikidata. https://www.wikidata.org/wiki/Q251347
  4. Haloperidol. In: PubChem Compound. CID 3559. https://pubchem.ncbi.nlm.nih.gov/compound/3559