Chemicals and Drugs

Histamine H2 Receptors

A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • H2 Receptors
  • Receptors, H2
  • Receptors, Histamine H2
  • H2 Receptors, Histamine

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

Indexing Annotation

receptors for the non-classical antihistaminics (HISTAMINE H2 ANTAGONISTS)

MeSH Record

History Note

87(77); was see under RECEPTORS, HISTAMINE 1977-86

MeSH Record

Previous Indexing

  • Histamine (1966-1976)
  • Receptors, Drug (1970-1976)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.670w.450w.400
  2. D12.776w.543w.750w.695w.355
  3. D12.776w.543w.750w.720w.480w.400

AMA Style

References

  1. National Library of Medicine. Histamine H2 Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011970. http://id.nlm.nih.gov/mesh/2026/D011970
  2. Histamine H2 Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q24786198