Chemicals and Drugs

Hydrocodone

Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.

Chemical Identity

Chemical Information

Molecular Formula
C18H21NO3
Molecular Weight
299.4 g/mol
CAS Registry No.
125-29-1
IUPAC Name
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
InChIKey
LLPOLZWFYMWNKH-CMKMFDCUSA-N
SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
MeSH Unique ID
D006853
Source
PubChem CID 5284569

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Dihydrocodeinone
  • Hydrocodon
  • Codinovo
  • Dicodid
  • Hycodan
  • Hycon
  • Hydrocodeinonebitartrate
  • Hydrocodone Bitartrate
  • Hydrocodone Tartrate (1:1), Hydrate (2:5)
  • Hydrocon
  • Robidone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse HYDROCODONE x refs with OXYCODONE x refs

MeSH Record

History Note

91(76); was see under CODEINE 1976-90

MeSH Record

Previous Indexing

  • Codeine/analogs & derivatives (1975)
  • Ethers, Cyclic (1973-1974)
  • Morphinans (1970-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.577.249.562.149w.287w
  2. D03w.605.497.607.204w.540w
  3. D03w.633.400.686.607.204w.540w
  4. D04w.615w.723w.795.576.149w.287w

AMA Style

References

  1. National Library of Medicine. Hydrocodone. Medical Subject Headings (MeSH). 2026. Unique ID D006853. http://id.nlm.nih.gov/mesh/2026/D006853
  2. Hydrocodone. In: Wikipedia. https://en.wikipedia.org/wiki/Hydrocodone
  3. Hydrocodone. In: Wikidata. https://www.wikidata.org/wiki/Q411441
  4. Hydrocodone. In: PubChem Compound. CID 5284569. https://pubchem.ncbi.nlm.nih.gov/compound/5284569