Chemicals and Drugs

Idoxuridine

An analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

Chemical Identity

Chemical Information

Molecular Formula
C9H11IN2O5
Molecular Weight
354.10 g/mol
CAS Registry No.
54-42-2
IUPAC Name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
InChIKey
XQFRJNBWHJMXHO-RRKCRQDMSA-N
SMILES
C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)CO)O
MeSH Unique ID
D007065
Source
PubChem CID 5905

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

32 entry terms
  • 5-Iodo-2'-deoxyuridine
  • 5-Iododeoxyuridine
  • IUdR
  • Iododeoxyuridine
  • 5 Iodo 2' deoxyuridine
  • 5 Iododeoxyuridine
  • Allergan 211
  • Herplex Liquifilm
  • Idoxuridine, 123I-Labeled
  • Idoxuridine, 125I-Labeled
  • Idoxuridine, 131I-Labeled
  • Idoxuridine, 3H-Labeled
  • Idoxuridine, Radical Ion (+1)
  • Idoxuridine, Radical Ion (1-)
  • Kerecide
  • NSC-39661
  • Oftan-IDU
  • SK&F-14287
  • Stoxil
  • 123I-Labeled Idoxuridine
  • 125I-Labeled Idoxuridine
  • 131I-Labeled Idoxuridine
  • 3H-Labeled Idoxuridine
  • Idoxuridine, 123I Labeled
  • Idoxuridine, 125I Labeled
  • Idoxuridine, 131I Labeled
  • Idoxuridine, 3H Labeled
  • Liquifilm, Herplex
  • NSC 39661
  • NSC39661
  • Oftan IDU
  • OftanIDU

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Previous Indexing

  • Antimetabolites (1966-1991)
  • Antiviral Agents (1966-1991)
  • Deoxyuridine (1966-1991)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.742.680.852w.300w.400w
  2. D13.570w.230w.430w.609w
  3. D13.570w.685.852w.300w.400w

AMA Style

References

  1. National Library of Medicine. Idoxuridine. Medical Subject Headings (MeSH). 2026. Unique ID D007065. http://id.nlm.nih.gov/mesh/2026/D007065
  2. Idoxuridine. In: Wikipedia. https://en.wikipedia.org/wiki/Idoxuridine
  3. Idoxuridine. In: Wikidata. https://www.wikidata.org/wiki/Q409765
  4. Idoxuridine. In: PubChem Compound. CID 5905. https://pubchem.ncbi.nlm.nih.gov/compound/5905