Structured Summary
Abstract
2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.
Chemical Identity
Chemical Information
- Molecular Formula
- C9H12N2O5
- Molecular Weight
- 228.20 g/mol
- CAS Registry No.
- 951-78-0
- IUPAC Name
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- InChIKey
- MXHRCPNRJAMMIM-SHYZEUOFSA-N
- SMILES
- C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O
- MeSH Unique ID
- D003857
- Source
- PubChem CID 13712
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- (beta 1-(2-Deoxyribopyranosyl))thymidine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an antimetabolite
MeSH Record
History Note
66(64)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Deoxyuridine. Medical Subject Headings (MeSH). 2026. Unique ID D003857. http://id.nlm.nih.gov/mesh/2026/D003857
- Deoxyuridine. In: Wikipedia. https://en.wikipedia.org/wiki/Deoxyuridine
- Deoxyuridine. In: Wikidata. https://www.wikidata.org/wiki/Q419140
- Deoxyuridine. In: PubChem Compound. CID 13712. https://pubchem.ncbi.nlm.nih.gov/compound/13712