Structured Summary
Abstract
Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.
Chemical Identity
Chemical Information
- Molecular Formula
- C7H15Cl2N2O2P
- Molecular Weight
- 261.08 g/mol
- CAS Registry No.
- 3778-73-2
- IUPAC Name
- N,3-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine
- InChIKey
- HOMGKSMUEGBAAB-UHFFFAOYSA-N
- SMILES
- C1CN(P(=O)(OC1)NCCCl)CCCl
- MeSH Unique ID
- D007069
- Source
- PubChem CID 3690
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
13 entry terms
- Iphosphamide
- Iso-Endoxan
- Isofosfamide
- Isophosphamide
- Iso Endoxan
- Asta Z 4942
- Holoxan
- NSC-109,724
- NSC-109724
- NSC 109,724
- NSC 109724
- NSC109,724
- NSC109724
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
86(75); was see under CYCLOPHOSPHAMIDE 1975-85
MeSH Record
Previous Indexing
- Cyclic P-Oxides (1972-1974)
- Ethylamines (1972-1974)
- Oxazines (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ifosfamide. Medical Subject Headings (MeSH). 2026. Unique ID D007069. http://id.nlm.nih.gov/mesh/2026/D007069
- Ifosfamide. In: Wikipedia. https://en.wikipedia.org/wiki/Ifosfamide
- Ifosfamide. In: Wikidata. https://www.wikidata.org/wiki/Q418560
- Ifosfamide. In: PubChem Compound. CID 3690. https://pubchem.ncbi.nlm.nih.gov/compound/3690