Chemicals and Drugs

Nitrogen Mustard Compounds

A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Compounds, Nitrogen Mustard
  • Mustard Compounds, Nitrogen

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with NITROGEN MUSTARD, a specific chemical

MeSH Hierarchy

Tree Number

  1. D02w.455w.526.728w.650w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Nitrogen Mustard Compounds. Medical Subject Headings (MeSH). 2026. Unique ID D009588. http://id.nlm.nih.gov/mesh/2026/D009588
  2. Nitrogen Mustard Compounds. In: Wikipedia. https://en.wikipedia.org/wiki/Nitrogen_mustard
  3. Nitrogen Mustard Compounds. In: Wikidata. https://www.wikidata.org/wiki/Q414004