Chemicals and Drugs

Melphalan

An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 4-(Bis(2-chloroethyl)amino)phenylalanine
  • L-PAM
  • Phenylalanine Mustard
  • Mustard, Phenylalanine
  • Alkeran
  • Medphalan
  • Merphalan
  • Sarcolysine
  • Sarkolysin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.526.728w.650w.594w
  2. D12.125w.072.050w.685w.500w

AMA Style

References

  1. National Library of Medicine. Melphalan. Medical Subject Headings (MeSH). 2026. Unique ID D008558. http://id.nlm.nih.gov/mesh/2026/D008558
  2. Melphalan. In: Wikipedia. https://en.wikipedia.org/wiki/Melphalan
  3. Melphalan. In: Wikidata. https://www.wikidata.org/wiki/Q2298283