Chemicals and Drugs

Interleukin-1alpha

An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • Hematopoietin-1
  • IL-1 alpha
  • Interleukin-1 alpha
  • Hematopoietin 1
  • Interleukin 1 alpha
  • Interleukin 1alpha

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2007(1988)

MeSH Record

Previous Indexing

  • Interleukin-1 (1988-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Interleukin-1alpha. Medical Subject Headings (MeSH). 2026. Unique ID D053582. http://id.nlm.nih.gov/mesh/2026/D053582
  2. Interleukin-1alpha. In: Wikidata. https://www.wikidata.org/wiki/Q24722716