Chemicals and Drugs

Interleukin-1beta

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Catabolin
  • IL-1 beta
  • Interleukin-1 beta
  • Interleukin 1 beta
  • Interleukin 1beta

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1981)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.374w.465w.010w.600
  2. D12.644w.276.374w.500w.400w.600
  3. D12.776w.467.374w.465w.010w.600
  4. D12.776w.467.374w.500w.400w.600
  5. D23.529.374w.465w.131w.600
  6. D23.529.374w.500w.400w.600

AMA Style

References

  1. National Library of Medicine. Interleukin-1beta. Medical Subject Headings (MeSH). 2026. Unique ID D053583. http://id.nlm.nih.gov/mesh/2026/D053583
  2. Interleukin-1beta. In: Wikidata. https://www.wikidata.org/wiki/Q24776617