Chemicals and Drugs

Islet Amyloid Polypeptide

A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Amlintide
  • Amylin
  • IAPP Protein
  • Insulinoma Amyloid Polypeptide
  • Pancreatic Amylin
  • Amylin, Pancreatic
  • Amyloid Polypeptide, Insulinoma
  • Amyloid Polypeptide, Islet
  • Polypeptide, Insulinoma Amyloid
  • Polypeptide, Islet Amyloid
  • IAPP Precursor
  • Insulinoma Amyloid Polypeptide Precursor
  • Islet Amyloid Polypeptide Precursor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Islet Amyloid Polypeptide. Medical Subject Headings (MeSH). 2026. Unique ID D058228. http://id.nlm.nih.gov/mesh/2026/D058228
  2. Islet Amyloid Polypeptide. In: Wikipedia. https://en.wikipedia.org/wiki/Amylin
  3. Islet Amyloid Polypeptide. In: Wikidata. https://www.wikidata.org/wiki/Q424643