Structured Summary
Abstract
A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
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Synonyms
7 entry terms
- Karyopherin
- Transportin
- Transportins
- Exportin
- Exportins
- Importin
- Importins
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2002; use KARYOPHERINS (NM) 1995-2001
MeSH Record
Previous Indexing
- Nuclear Proteins (1995-2001)
- Receptors, Cytoplasmic and Nuclear (1995-2001)
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References
- National Library of Medicine. Karyopherins. Medical Subject Headings (MeSH). 2026. Unique ID D028884. http://id.nlm.nih.gov/mesh/2026/D028884
- Karyopherins. In: Wikipedia. https://en.wikipedia.org/wiki/Karyopherin
- Karyopherins. In: Wikidata. https://www.wikidata.org/wiki/Q3193641