Chemicals and Drugs

Leucine Enkephalin

One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 5-Leucine Enkephalin
  • Enkephalin, Leucine
  • Leu(5)-Enkephalin
  • Leu-Enkephalin
  • 5 Leucine Enkephalin
  • Enkephalin, 5-Leucine
  • Leu Enkephalin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

83

MeSH Record

Previous Indexing

  • Enkephalins (Aug 1977-1982)
  • Nerve Tissue Proteins (1966-Jul 1977)
  • Peptides (1966-Jul 1977)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Leucine Enkephalin. Medical Subject Headings (MeSH). 2026. Unique ID D004743. http://id.nlm.nih.gov/mesh/2026/D004743
  2. Leucine Enkephalin. In: Wikidata. https://www.wikidata.org/wiki/Q21120419