Chemicals and Drugs

Leukocidins

Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Leukocidin Proteins
  • Proteins, Leukocidin
  • Leucocidin
  • Leukocidin

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/antag permitted but consider also ANTITOXINS

MeSH Record

History Note

78; was LEUKOCIDIN 1965-77

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.695w.750w

AMA Style

References

  1. National Library of Medicine. Leukocidins. Medical Subject Headings (MeSH). 2026. Unique ID D007956. http://id.nlm.nih.gov/mesh/2026/D007956
  2. Leukocidins. In: Wikipedia. https://en.wikipedia.org/wiki/Leukocidin
  3. Leukocidins. In: Wikidata. https://www.wikidata.org/wiki/Q16889545