Structured Summary
Abstract
A receptor for HISTOCOMPATIBILITY ANTIGENS CLASS I that also functions as a receptor for the UL18 protein, an MHC class I homolog expressed by human CYTOMEGALOVIRUS. It consists of four Ig-like C2 domains and is expressed primarily by B-cells and MONOCYTES, as well as DENDRITIC CELLS; its interaction with MHC1 functions to down-regulate the immune response.
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Synonyms
13 entry terms
- CD85 Antigen
- CD85J Antigen
- ILT2 Protein
- Immunoglobulin-like Transcript 2 Protein
- LILRB1
- LIR-1 Protein
- Leukocyte Ig-like Receptor B1
- Antigen, CD85
- Antigen, CD85J
- Immunoglobulin like Transcript 2 Protein
- LIR 1 Protein
- Leukocyte Ig like Receptor B1
- Leukocyte Immunoglobulin like Receptor B1
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Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
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History Note
2018
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Previous Indexing
- Antigens, CD (1997-2017)
- Receptors, Immunologic (1997-2017)
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AMA Style
References
- National Library of Medicine. Leukocyte Immunoglobulin-like Receptor B1. Medical Subject Headings (MeSH). 2026. Unique ID D000075362. http://id.nlm.nih.gov/mesh/2026/D000075362
- Leukocyte Immunoglobulin-like Receptor B1. In: Wikidata. https://www.wikidata.org/wiki/Q21120812