Chemicals and Drugs

Leukotrienes

A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.

MeSH Record

Classification

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See Also

MeSH Record

Synonyms

1 entry terms
  • Leukotriene

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Arachidonic Acids (1979-1988)
  • Leukotrienes B (1983-1988)
  • SRS-A (1979-1988)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 90

AMA Style

References

  1. National Library of Medicine. Leukotrienes. Medical Subject Headings (MeSH). 2026. Unique ID D015289. http://id.nlm.nih.gov/mesh/2026/D015289
  2. Leukotrienes. In: Wikipedia. https://en.wikipedia.org/wiki/Leukotriene
  3. Leukotrienes. In: Wikidata. https://www.wikidata.org/wiki/Q424190