Diseases

Lewy Body Disease

A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • Cortical Lewy Body Disease
  • Dementia, Lewy Body
  • Diffuse Lewy Body Disease
  • Lewy Body Dementia
  • Lewy Body Disease, Cortical
  • Lewy Body Disease, Diffuse
  • Lewy Body Type Senile Dementia

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

LEWY BODY PARKINSON DISEASE see PARKINSON DISEASE is also available

MeSH Record

History Note

2000; use PARKINSON DISEASE 1992-1999; for DIFFUSE LEWY BODY DISEASE & LEWY BODY DISEASE, DIFFUSE use PARKINSON DISEASE 1992-1999

MeSH Record

Previous Indexing

  • Alzheimer Disease (1979-1999)
  • Parkinson Disease (1977-1999)
  • Parkinson Disease, Secondary (1984-1999)

MeSH Hierarchy

Tree Numbers

  1. C10w.228w.140w.079w.862w.400w
  2. C10w.228w.140w.380w.422w
  3. C10w.228w.662w.600w.200w
  4. C10w.574w.928w.500w
  5. F03w.615w.400w.512w

AMA Style

References

  1. National Library of Medicine. Lewy Body Disease. Medical Subject Headings (MeSH). 2026. Unique ID D020961. http://id.nlm.nih.gov/mesh/2026/D020961
  2. Lewy Body Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Lewy_body_dementia
  3. Lewy Body Disease. In: Wikidata. https://www.wikidata.org/wiki/Q1331905