Chemicals and Drugs

Mediator Complex Subunit 1

A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

16 entry terms
  • DRIP205
  • Mediator of RNA Polymerase II Transcription Subunit 1
  • PPAR-Binding Protein
  • Peroxisome Proliferator-Activated Receptor Binding Protein
  • RB18A
  • TR-Associated Protein P220
  • TRAP220
  • TRIP2 (Thyroid Receptor Interacting Protein 2)
  • Thyroid Hormone Receptor Associated Protein 220
  • Thyroid Receptor Interacting Protein 2
  • Vitamin D Receptor-Interacting Protein Complex Component DRIP205
  • p53 Regulatory Protein RB18A
  • PPAR Binding Protein
  • Peroxisome Proliferator Activated Receptor Binding Protein
  • TR Associated Protein P220
  • Vitamin D Receptor Interacting Protein Complex Component DRIP205

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010(1998)

MeSH Hierarchy

Tree Numbers

  1. D05.500w.374w.750
  2. D12.644w.360.024w.309w.750
  3. D12.644w.360.024w.314.049
  4. D12.776w.157w.057w.072w.750
  5. D12.776w.157w.057w.080.049
  6. D12.776w.476.024w.388w.750
  7. D12.776w.476.024w.394.049
  8. D12.776w.660w.551w.750
  9. D12.776w.660w.675.049
  10. D12.776w.930w.617.049

AMA Style

References

  1. National Library of Medicine. Mediator Complex Subunit 1. Medical Subject Headings (MeSH). 2026. Unique ID D056913. http://id.nlm.nih.gov/mesh/2026/D056913
  2. Mediator Complex Subunit 1. In: Wikidata. https://www.wikidata.org/wiki/Q83136190