Diseases

Megalencephaly

A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with HYDROCEPHALUS; SUBDURAL EFFUSION; ARACHNOID CYSTS; or is part of a genetic condition (e.g., ALEXANDER DISEASE; SOTOS SYNDROME).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with HYDROCEPHALUS; SUBDURAL EFFUSION; ARACHNOID CYSTS; or is part of a genetic condition (e.g., ALEXANDER DISEASE; SOTOS SYNDROME).

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • Macrocephaly
  • Megacephaly
  • Megalocephaly
  • Macrocephalies
  • Megacephalies
  • Megalencephalies
  • Megalocephalies

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2011; use Macrocephaly 2011-2014, Megalencephaly was under Macrocephaly 2011-2014

MeSH Record

Previous Indexing

  • Craniofacial Abnormalities (1994-2010)
  • Head/abnormalities (1970-2010)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Megalencephaly. Medical Subject Headings (MeSH). 2026. Unique ID D058627. http://id.nlm.nih.gov/mesh/2026/D058627
  2. Megalencephaly. In: Wikipedia. https://en.wikipedia.org/wiki/Megalencephaly
  3. Megalencephaly. In: Wikidata. https://www.wikidata.org/wiki/Q10748814