Chemicals and Drugs

Member 4 Solute Carrier Family 12

K-Cl cotransporter ubiquitously expressed with higher expression levels in ERYTHROCYTES of ANEMIA, SICKLE CELL. It mediates active potassium and chloride cotransport across the plasma membrane and contributes to cell volume homeostasis

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

K-Cl cotransporter ubiquitously expressed with higher expression levels in ERYTHROCYTES of ANEMIA, SICKLE CELL. It mediates active potassium and chloride cotransport across the plasma membrane and contributes to cell volume homeostasis

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MeSH Record

Synonyms

16 entry terms
  • Electroneutral Potassium-Chloride Cotransporter 1
  • Erythroid K-Cl Cotransporter 1
  • KCC1 Cotransporter
  • KCC1 Protein
  • Potassium-Chloride Cotransporter 1
  • SLC12A4 Protein
  • SLC12A4 Proteins
  • Solute Carrier Family 12 (Potassium Chloride Transporters), Member 4 Protein
  • Solute Carrier Family 12 Member 4
  • Solute Carrier Family 12, Member 4
  • Cotransporter, KCC1
  • Electroneutral Potassium Chloride Cotransporter 1
  • Erythroid K Cl Cotransporter 1
  • Potassium Chloride Cotransporter 1
  • Protein, KCC1
  • Protein, SLC12A4

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

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AMA Style

References

  1. National Library of Medicine. Member 4 Solute Carrier Family 12. Medical Subject Headings (MeSH). 2026. Unique ID D064507. http://id.nlm.nih.gov/mesh/2026/D064507
  2. Member 4 Solute Carrier Family 12. In: Wikidata. https://www.wikidata.org/wiki/Q21124441