Chemicals and Drugs

Meprobamate

A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Chemical Identity

Chemical Information

Molecular Formula
C9H18N2O4
Molecular Weight
218.25 g/mol
CAS Registry No.
57-53-4
IUPAC Name
[2-(carbamoyloxymethyl)-2-methylpentyl] carbamate
InChIKey
NPPQSCRMBWNHMW-UHFFFAOYSA-N
SMILES
CCCC(C)(COC(=O)N)COC(=O)N
MeSH Unique ID
D008620
Source
PubChem CID 4064

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Dapaz
  • Equanil
  • Meprospan
  • Miltown
  • Méprobamate Richard
  • Tranmep
  • Visano

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D02w.241w.081.251w.510w

MeSH Record

NLM Classification

QV 77.9

AMA Style

References

  1. National Library of Medicine. Meprobamate. Medical Subject Headings (MeSH). 2026. Unique ID D008620. http://id.nlm.nih.gov/mesh/2026/D008620
  2. Meprobamate. In: Wikipedia. https://en.wikipedia.org/wiki/Meprobamate
  3. Meprobamate. In: Wikidata. https://www.wikidata.org/wiki/Q418351
  4. Meprobamate. In: PubChem Compound. CID 4064. https://pubchem.ncbi.nlm.nih.gov/compound/4064